Two-alarm fire guts USF marine science lab as 200 firefighters battle blaze overnight

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, May 4, 2026 
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A two-alarm fire tore through the Marine Science Laboratory at the University of South Florida's St. Petersburg campus Saturday, drawing roughly 200 firefighters and more than 60 emergency units to a scene marked by green flames shooting from the roof and thick black smoke visible for miles.

No one was injured. But the building, more than 80 years old, may never reopen. Officials now describe the structure as a probable total loss, with decades of faculty research potentially destroyed.

St. Petersburg Fire District Chief Michael Lewis told Fox 13 that crews would monitor the scene overnight, working through a painstaking process to confirm that no active fire was threatening hazardous materials stored inside the lab.

"We are just mopping up some hotspots. We are going through and confirming all of the hazardous materials that were on scene. This is going to be a very extensive process to go through, confirm that there is no active fire impinging upon any of the hazardous materials."

Lewis added that there were no hazards to the surrounding areas and reassured nearby residents they were safe. The fire was largely extinguished by around 9 p.m., Fox News reported, but the damage was already catastrophic. The entire roof had burned off.

Witness warned building could collapse

Ashley Briscoe, a witness who was leaving a building nearby when the fire broke out, described a harrowing scene. Emergency personnel urged people to move quickly, warning the burning structure could topple.

"I was right next to the building. They were even saying that the building could fall over. As we're walking out, they're like, 'My gosh, hurry up, the building can possibly topple over.' That's very scary."

Video footage shared by the Tampa Bay Times on social media showed the green flames, likely the result of chemical combustion, pouring from the building's roof as alarms blared. Aerial footage captured the enormous plume of smoke filling the sky above St. Petersburg. A separate clip showed emergency vehicles lining the campus as sirens sounded.

The blaze was first reported when a witness spotted flames from outside the building. Within minutes, the response escalated to a two-alarm call, bringing the full weight of the St. Petersburg fire apparatus to bear on a single campus structure.

Florida has seen no shortage of large-scale fire emergencies in recent months. Massive wildfires across Georgia and Florida burned more than 55,000 acres earlier this year, stretching firefighting resources across the Southeast.

Decades of research at risk

The Marine Science Laboratory housed faculty research labs, and the fire's destruction may extend well beyond bricks and roofing. Frank Biafora, interim associate dean at USF St. Petersburg, described the loss in stark terms.

"We have faculty members who have research labs there. This looks like total devastation. We've all been checking in on each other."

That quote, reported by the New York Post, captures the scale of what the university now faces. More than 50 units of first responders arrived to fight the fire, and the structural damage, a crumpled roof, extensive water damage throughout, left little standing.

USF President Moez Limayem acknowledged the severity of the situation. In a statement reported by the Associated Press, Limayem wrote that recovery teams were already coordinating with the College of Marine Science.

"Our recovery teams are working with the College of Marine Science to prioritize key research material and equipment for salvage assessment when the building is cleared."

Officials confirmed no hazardous materials were released during the fire, a fact that likely spared the surrounding neighborhood from a far worse outcome. The building was safely evacuated, and everyone was accounted for once the fire was brought under control.

The cost of losing a working research facility, equipment, data, years of accumulated scientific work, is the kind of damage that doesn't show up in an insurance claim. The human toll was mercifully zero. The institutional toll remains to be counted.

Cause unknown, investigation ahead

Officials were preparing to launch an investigation into what caused the fire. No cause has been stated publicly, and it may take considerable time to determine one, given the extent of the destruction and the presence of hazardous materials that must be catalogued and secured before investigators can fully access the site.

The Washington Times reported that evacuations were ordered during the blaze and that the destruction was extensive, consistent with accounts from every other outlet covering the fire. The building could be a total loss.

The fire affected only the Marine Science Laboratory. The nearby Ocean Research Lab was not damaged. University officials said students should report to class Monday, a signal that the broader campus operations would continue despite the loss of one of its oldest structures.

The response of 200 firefighters to a single building fire on a university campus speaks to the seriousness of the situation. When a structure holds chemicals and the roof is already gone, the margin for error narrows fast. Florida's firefighters have faced extraordinary demands in recent months, and Saturday's response was another reminder of the risks they absorb on behalf of the communities they serve.

The building's age, over 80 years, raises its own set of questions. Older infrastructure on university campuses across the country often houses sensitive materials and expensive equipment without the fire-suppression systems found in modern construction. Whether that played any role here remains unknown.

Large-scale emergency responses have become a recurring feature of the news cycle. From mass-casualty transit incidents near the Pentagon to campus fires threatening hazardous materials, first responders continue to carry the weight of aging infrastructure and unpredictable emergencies.

What comes next

Lewis said crews would remain on scene overnight to monitor for flare-ups and continue the process of confirming that all hazardous materials were accounted for. That kind of methodical, unglamorous work, checking every container, scanning every corner of a gutted building, is the part of firefighting that never makes the highlight reel.

For USF's College of Marine Science, the path forward likely involves temporary relocations, insurance battles, and the painful task of determining what, if anything, can be salvaged from the wreckage. President Limayem's statement suggested the university was already moving in that direction.

The broader question, whether an 80-year-old building storing hazardous materials had adequate fire protection, is one the investigation will need to answer. Crisis management and emergency preparedness are only as strong as the infrastructure and protocols behind them.

Two hundred firefighters kept a bad situation from becoming a catastrophe. The building is gone. The research may be gone. But every person walked out alive. That's the line between a disaster and a tragedy, and on Saturday in St. Petersburg, the men and women on the hose held it.

About Jack Newsome

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